BBC health and science correspondent James Gallagher investigates the current possibilities and scientific progress related to finding a cure for Alzheimer’s disease. The focus is on recent advancements in understanding the pathology of neurodegeneration, including efforts to identify effective treatments that could halt or reverse cognitive decline. Researchers are exploring various approaches, such as immunotherapies, gene editing techniques, and novel pharmaceuticals aimed at targeting amyloid plaques and tau protein accumulation, which are hallmarks of the disease. While these strategies have shown promise in early trials, none have yet been conclusively proven to cure Alzheimer’s, and ongoing research continues to face significant scientific challenges. The aim of such investigations is to develop interventions that can significantly improve patient outcomes and potentially eradicate disease progression, but the complexity of the brain and individual variability remain major hurdles to achieving a definitive cure.